These Popular Supplements Are Sold With Anti-Aging Claims. Here's What Science Says.

Anti-aging supplements such as NAD+, NMN, nicotinamide riboside, and resveratrol are heavily marketed, but solid evidence for real longevity benefits in humans is still limited.

NAD+ is an important cellular coenzyme, and NMN and NR can raise NAD+ levels in people, but that biomarker change does not yet prove anti-aging effects.

Resveratrol is also sold as an anti-aging ingredient, yet the strongest results mostly come from animal studies rather than human clinical outcomes.

For skincare, the evidence is especially weak: products may promise age-reversal, but proven long-term benefits are scarce compared with established options like retinoids and niacinamide.