Popular Vitamin B3 Supplements May Help Cancer Cells Survive, Scientists Warn

A Case Western Reserve study found that common NAD+‑boosting supplements can help pancreatic cancer cells resist chemotherapy.

In lab and mouse tests, NMN, NR, and NAM increased cancer cell energy, lowered tumor oxidative stress, and reduced DNA damage from treatment.

The supplements decreased effectiveness of oxaliplatin, 5‑fluorouracil, and gemcitabine against pancreatic tumors.

Researchers recommend screening cancer patients for supplement use and conducting further clinical studies.