A Common Vitamin Could Hold the Key to Treating Fatty Liver Disease

Researchers found that microRNA-93 is elevated in MASLD and helps drive fatty liver disease by suppressing SIRT1 and related metabolic pathways.

In mouse studies, blocking miR-93 or giving niacin (vitamin B3) reduced liver fat buildup and improved metabolic function.

The findings point to a specific molecular target in fatty liver disease and suggest an already approved vitamin could be repurposed as a treatment.

A clinical trial is now testing niacin in patients, which could speed translation if the results hold up.