Roots of Many Miscarriages Could Trace Back to Before the Mother Is Even Born

A large IVF embryo study linked inherited variants in egg-cell meiosis genes to higher risk of chromosomal errors that can lead to miscarriage.

Researchers analyzed genetic data from nearly 140,000 IVF embryos and their parents.

Variants in genes that control chromosome pairing and recombination were associated with maternal meiotic aneuploidy and embryo loss.

The findings may help explain why some people face higher pregnancy-loss risk and improve fertility care.