New Vitamin B12-Based Therapy Could Change How Brain Cancer Is Treated

An early study suggests nitrosylcobalamin, a vitamin B12-derived nitric oxide donor, may help treat glioblastoma.

In animal studies, the compound crossed the blood-brain barrier and accumulated in brain tumor tissue.

In cell studies, it worked synergistically with TRAIL and temozolomide against glioblastoma cells.

The finding could matter because many brain cancer drugs struggle to reach tumors behind the blood-brain barrier.