JANUS: Anatomy-Conditioned Gating for Robust CT Triage Under Distribution Shift

Researchers introduced JANUS, a physiology-guided dual-stream CT triage model that fuses visual features with anatomy-based priors.

JANUS outperformed reproduced baselines on the MERLIN test set and an external dataset, improving macro-AUROC, AUPRC, and calibration.

Under domain shift, it more often reduced high-confidence false positives than true positives, which is important for safer real-world screening.

The approach is designed to make automated CT triage more dependable across hospitals and patient populations.