New Strategy Shows Promise Against the Deadliest Brain Cancer

University of Virginia researchers report an experimental glioblastoma therapy that uses MRI-guided focused ultrasound and microbubbles to temporarily open the blood-brain barrier.

The opening lets nanoparticles deliver microRNAs into the brain, enabling treatment of hard-to-reach tumor cells.

In animal models, the approach slowed glioblastoma growth and extended survival.

The method could support multi-target brain cancer therapy by overcoming one of the biggest barriers to treatment.