Scientists Discover Natural Molecule That Stops Alzheimer’s Protein Clumps From Forming

Researchers found that the natural metabolite L-arginine keeps Tau protein droplets functional while reducing their conversion into Alzheimer’s-linked fibrils.

L-arginine stabilizes Tau-containing liquid condensates and suppresses fibril growth at droplet surfaces.

Importantly, it preserves the droplets’ normal role in supporting microtubule assembly.

The finding points to a more selective Alzheimer’s therapy strategy that blocks toxic aggregation without disrupting healthy cellular functions.