Scientists Reveal Biological Signal Behind Mysterious Alzheimer’s Drug Side Effect

Study research published published in Nature Communications.

ARIA can cause brain swelling or small areas of bleeding visible on MRI linked to MRI-detected brain swelling or microbleeds.

Research team team analyzed blood samples from lecanemab-treated patients patients treated at Norton Neuroscience Institute.

T cells patients who developed ARIA had increased levels of a specific subset of T cells identified in patient blood using genetic and metabolic profiling.

Immune signal the immune signal can be measured in blood rather than by brain biopsy detectable through a standard blood test.